細(xì)胞名稱

人神經(jīng)母細(xì)胞瘤細(xì)胞SK-N-DZ

英文名稱

SK-N-DZ

形態(tài)特性

成神經(jīng)細(xì)胞樣

生長(zhǎng)特性

貼壁生長(zhǎng)

種屬

人

組織

大腦

培養(yǎng)體系

DMEM＋10% FBS＋1% P/S 氣相：空氣，95%；CO2，5%。  溫度：37℃

STR

Amelogenin X CSF1PO 12 D3S1358 17 D5S818 12 D7S820 12,13 D8S1179 12,13 D13S317 8,11 D16S539 9,11 D18S51 15,17 D21S11 29,31 FGA 18,22 Penta D 9,14 Penta E 7,10 TH01 6,9 TPOX 8 vWA 16,18

簡(jiǎn)介

SK-N-DZ are neuroblasts that were isolated from the brain of a 2-year-old, White female patient with neuroblastoma.SK-N-DZ are neuroblasts that were isolated from the brain of a 2-year-old, White female patient with neuroblastoma. Expression of the N-myc gene product was reduced in differentiated SK-N-DZ cells as compared with undifferentiated cells. Expression of the c-src gene product, pp60c-src was enhanced in differentiated SK-N-DZ cells as was tyrosine phosphorylation of cellular proteins. The cells exhibit moderate MDR1 expression. Retinoic acid induces differentiation in this line.

傳代方法

建議第一次1:2傳代

凍存條件

90 FBS+10% DMSO, 推薦無血清凍存液 (CX001)

用途

僅限于科學(xué)研究，不可作為動(dòng)物或人類疾病的治療產(chǎn)品使用。

備注

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